HPLC Quantification of Cytotoxic Compounds fromAspergillus niger

Determination of Phenolic Compounds in Pinus eldarica by HPLC

Background: The antioxidant components have been identified in some pine species. Antioxidant properties of proantocyanidins reduce free radicals induced by DNA fragmentation and lipid proxidation and also proanthocyanidines could curb lipid peroxidation. Objective: In this study, we analyzed different parts of Pinus eldarica (bark, seed and needle) and assessed their antioxidant contents. ...

HPLC-MS/MS of Highly Polar Compounds

Cytotoxic Compounds from Aloe megalacantha.

Phytochemical investigation of the ethyl acetate extract of the roots of Aloe megalacantha led to the isolation of four new natural products-1,8-dimethoxynepodinol (1), aloesaponarin III (2), 10-O-methylchrysalodin (3) and methyl-26-O-feruloyl-oxyhexacosanate (4)-along with ten known compounds. All purified metabolites were characterized by NMR, mass spectrometric analyses and comparison with l...

Cytotoxic Compounds from Brucea mollis

Ten compounds, including soulameanone (1), isobruceine B (2), 9-methoxy-canthin-6-one (3), bruceolline F (4), niloticine (5), octatriacontan-1-ol (6), bombiprenone (7), α-tocopherol (8), inosine (9), and apigenin 7-O-β-D-glucopyranoside (10), were isolated from the leaves, stems, and roots of Brucea mollis Wall. ex Kurz. Their structures were determined using one-and two-dimensional NMR spectro...

Cytotoxic compounds from Laurencia pacifica

BACKGROUND The current investigation sought to explore the nature of the secondary metabolites in the algae, Laurencia pacifica. RESULTS This report details the first isolation of the sesquiterpenes isoaplysin (1), isolaurenisol (2), debromoisolaurinterol (3), debromoaplysinol (4), laur-11-en-10-ol (5), 10α-hydroxyldebromoepiaplysin (6), and the previously unknown 10-bromo-3,7,11,11-tetrameth...